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Combinatorial Chemistry

Combinatorial Chemistry

The Combinatorial Chemistry is a scientific method in which a very large number of chemical entities are synthesized by condensing a small number of chemical compounds together in all combinations defined by a small set of chemical reactions.

Online available information resources on combinatorial chemistry.

Further information categories about related topics are listed in the navigation menu on the left side of these page.

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General Information

Combinatorial Chemistry Review
An overview of combinatorial synthesis, including polymers and linkers for solid-phase synthesis, determination of product structure, solution-phase synthesis and applications of combichem - [e]

Combinatorial Index Website
Information on Combinatorial Chemistry, eBook - [USA > e]

[Gen] [Det] [Lec] [Nom] [Soft] [Jour] [Research]

Details

Activation of C-H Bonds alpha to Nitriles for Combinatorial Chemistry
Ruthenium-Catalyzed Aldol and Michael Reactions of Polymer-Supported Nitriles. Synlett, 2001. Thieme - [D > e]

[Gen] [Det] [Lec] [Nom] [Soft] [Jour] [Research]

Lecture Notes, Tutorials

Combinatorial and Fragment-Based Ligand Design
Lecture notes - Format: PDF - [D > e]

Combinatorial Chemistry and Multiple Parallel Synthesis
eBook. Wiley - [e]

Combinatorial Chemistry and Solid Phase Synthesis
Lecture notes - [A > d, e]

Combinatorial Chemistry and the Grid
Grid Computing - Making the Global Infrastructure a Reality. eBook - [UK > e]

Combinatorial Chemistry in Drug Research
Lecture notes - Format: PDF - [D > e]

Combinatorial Chemistry Technology
Lecture notes - Format: PDF - [D > e]

[Gen] [Det] [Lec] [Nom] [Soft] [Jour] [Research]

Nomenclature

Glossary
... of Terms Used in Combinatorial Chemistry. IUPAC - [USA > e]

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Software and Programs

SmiLib
... is a free, platform indepentend software tool for rapid combinatorial library enumeration in the flexible and portable SMILES notation. SmiLib enumerates combinatorial libraries at rates of approximately 9,000,000 molecules per second on fast computers - [D > e]

[Gen] [Det] [Lec] [Nom] [Soft] [Jour] [Research]

Journals

Combinatorial Chemistry
... is revolutionising the approach to synthetic organic chemistry and other fields, and is greatly enhancing the rate of discovery of new molecular entities. Elsevier - [NL > e]

Combinatorial Chemistry & High Throughput Screening
... publishes full length original research articles and reviews describing various topics in combinatorial chemistry (e.g. small molecules, peptide, nucleic acid or phage display libraries) and/or high throughput screening (e.g. developmental, practical or theoretical). Bentham Science Publishers - [e]

Journal of Combinatorial Chemistry
... is an interdisciplinary journal that opens up channels of information for synthetic organic chemists, medicinal and analytical chemists, pharmaceutical scientists, biotechnologists, computational chemists, material scientists, and agrochemists. ACS - [USA > e]

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Research facilities and departments

Japan
Japan Combinatorial Chemistry Focus Group, JCCF - [JP > jp, e]

Further Information:

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Related Books and Scientific Literature: Combinatorial Chemistry:

Willi Bannwarth, Berthold Hinzen

Combinatorial Chemistry. From Theory to Application.
(Methods and Principles in Medicinal Chemistry).

The new edition of this practice--oriented handbook features thoroughly updated contents, including recent developments in parallel synthesis. A new chapter on screening complements the overview of combinatorial strategy and synthetic methods. "Experimental details and complete reaction data [...] are a constant theme running through this work" (Angewandte Chemie) "Recommended to newcomers in the field of combinatorial chemical synthesis because of its broad scope" (Journal of the American Chemical Society).

Wiley-VCH; 2006