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Journal of Enzyme Inhibition and Medicinal Chemistry - Aktuelle Forschungsartikel

Aktuelle Forschungsartikel: Medizinische Chemie

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Journal of Enzyme Inhibition and Medicinal Chemistry - Verlag: Informa

Das Journal ist ein internationales und interdisziplinäres Forum zur Veröffentlichung neuer Kenntnisse und Erkenntnisse über Enzym-Hemmer und hemmende Prozesse sowie Agonist/Antagonist-Rezeptor-Wechselwirkungen in der Entwicklung von Arzneimitteln und Anti-Krebs-Wirkstoffen.

Wissenschaftliche Fachartikel:

The protective effect of docosahexaenoic acid on the bilirubin neurotoxicity

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 16 May 2012 | 6:29 pm

Conformation depends on 4D-QSAR analysis using EC–GA method: pharmacophore identification and bioactivity prediction of TIBOs as non-nucleoside reverse transcriptase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-16, Early Online.

Posted on 16 May 2012 | 6:29 pm

Synthesis of purine homo-N-nucleosides modified with coumarins as free radicals scavengers*

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-11, Early Online.

Posted on 16 May 2012 | 6:29 pm

Impacts of some antibiotics on human serum paraoxonase 1 activity

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 16 May 2012 | 6:29 pm

The effect of angiotensin-converting enzyme inhibition by captopril on respiratory mechanics in healthy rats

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 16 May 2012 | 6:29 pm

Design, synthesis and biological evaluation of novel L-isoserine tripeptide derivatives as aminopeptidase N inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-10, Early Online.

Posted on 30 April 2012 | 5:29 pm

A comparison of the reactivating efficacy of a novel bispyridinium oxime K203 with currently available oximes in VX agent-poisoned rats

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 30 April 2012 | 5:29 pm

Synthesis, activity evaluation, and docking analysis of barbituric acid aryl hydrazone derivatives as RSK2 inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 30 April 2012 | 5:28 pm

Biotransformation of dehydroepiandrosterone with Macrophomina phaseolina and ?-glucuronidase inhibitory activity of transformed products

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 348-355, June 2012.

Posted on 27 April 2012 | 11:31 am

Pharmacophore modelling and atom-based 3D-QSAR studies on N-methyl pyrimidones as HIV-1 integrase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 339-347, June 2012.

Posted on 27 April 2012 | 11:31 am

Inhibition of carbonic anhydrase isozymes I and II with natural products extracted from plants, mushrooms and honey

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 395-402, June 2012.

Posted on 27 April 2012 | 11:31 am

Association of ?-amyloid peptide fragments with neuronal nitric oxide synthase: Implications in the etiology of Alzheimers disease

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 356-364, June 2012.

Posted on 27 April 2012 | 11:31 am

Synthesis, characterization and biocidal activity of some transition metal(II) complexes with isatin salicylaldehyde acyldihydrazones

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 319-329, June 2012.

Posted on 27 April 2012 | 11:31 am

Antiproliferative effects of metal complexes of new isatin hydrazones against HCT116, MCF7 and HELA tumour cell lines

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 330-338, June 2012.

Posted on 27 April 2012 | 11:31 am

A new class of 2-(4-cyanophenyl amino)-4-(6-bromo-4-quinolinyloxy)-6-piperazinyl (piperidinyl)-1,3,5-triazine analogues with antimicrobial/antimycobacterial activity

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 370-379, June 2012.

Posted on 27 April 2012 | 11:31 am

Constituents with tyrosinase inhibitory activities from branches of Ficus erecta var. sieboldii King

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 390-394, June 2012.

Posted on 27 April 2012 | 11:31 am

Studies on collagen-tannic acid-collagenase ternary system: Inhibition of collagenase against collagenolytic degradation of extracellular matrix component of collagen

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 451-457, June 2012.

Posted on 27 April 2012 | 11:31 am

Studies on the cytotoxic, apoptotic and antitumoral effects of Au(III) and Pt(II) complexes of 1, 10-phenanthroline on V79 379A and A549 cell lines

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 458-466, June 2012.

Posted on 27 April 2012 | 11:31 am

Synthesis and structure–activity relationship of novel conformationally restricted analogues of serotonin as 5-HT6 receptor ligands

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 443-450, June 2012.

Posted on 27 April 2012 | 11:31 am

Synthesis of novel benzoxanthone analogues as non-Camptothecin topoisomerase I inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 437-442, June 2012.

Posted on 27 April 2012 | 11:31 am

Synthesis and antioxidant activity evaluations of melatonin-based analogue indole-hydrazide/hydrazone derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 428-436, June 2012.

Posted on 27 April 2012 | 11:31 am

Synthesis and antidiabetic activity of morpholinothiazolyl-2,4-thiazolidindione derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 419-427, June 2012.

Posted on 27 April 2012 | 11:31 am

Cytotoxicity and DNA interactions of some platinum(II) complexes with substituted benzimidazole ligands

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 413-418, June 2012.

Posted on 27 April 2012 | 11:31 am

Effects of dopaminergic compounds on carbonic anhydrase isozymes I, II, and VI

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 365-369, June 2012.

Posted on 27 April 2012 | 11:30 am

Metal-based new sulfonamides: Design, synthesis, antibacterial, antifungal, and cytotoxic properties

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 27, Issue 3, Page 403-412, June 2012.

Posted on 27 April 2012 | 11:30 am

Effect of the o-methyl catechols apocynin, curcumin and vanillin on the cytotoxicity activity of tamoxifen

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 23 April 2012 | 10:32 pm

Interaction of superoxide dismutase with the glycine zipper regions of ?-amyloid peptides: Is there an implication towards Alzheimer’s disease and oxidative stress?

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 23 April 2012 | 10:32 pm

The efficient expression of human fibroblast collagenase in Escherichia coli and the discovery of flavonoid inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 23 April 2012 | 10:31 pm

A new depsidone of Lobaria pulmonaria with acetylcholinesterase inhibition activity

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-3, Early Online.

Posted on 18 April 2012 | 5:21 pm

Synthesis and carbonic anhydrase inhibitory properties of novel coumarin derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 18 April 2012 | 5:21 pm

The effect of some antineoplastic agents on glutathione S-transferase from human erythrocytes

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 18 April 2012 | 5:21 pm

Famotidine inhibits glycogen synthase kinase-3?: An investigation by docking simulation and experimental validation

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 18 April 2012 | 5:21 pm

Inhibitory effect of Terminalia chebula Retz. fruit extracts on digestive enzyme related to diabetes and oxidative stress

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-9, Early Online.

Posted on 18 April 2012 | 5:20 pm

Direct antiproliferative effect of nonsteroidal 17?-hydroxysteroid dehydrogenase type 1 inhibitors in vitro

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-9, Early Online.

Posted on 3 April 2012 | 6:21 pm

Quinazoline-sulfonamides as potential antitumor agents: synthesis and biological testing

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-8, Early Online.

Posted on 2 April 2012 | 6:32 pm

Synthesis and biological evaluation of 5-fluoroquinolone-3-carboxylic acids as potential HIV-1 integrase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 2 April 2012 | 6:32 pm

Structure-based drug discovery of carbonic anhydrase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-14, Early Online.

Posted on 2 April 2012 | 6:31 pm

Inhibition of cysteine proteases by a natural biflavone: behavioral evaluation of fukugetin as papain and cruzain inhibitor

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-10, Early Online.

Posted on 2 April 2012 | 6:31 pm

Tyrosinase inhibitory activities of the compounds isolated from Neolitsea aciculata (Blume) Koidz.

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 2 April 2012 | 6:31 pm

2,2?-dithienyl diselenide, an organoselenium compound, elicits antioxidant action and inhibits monoamine oxidase activity in vitro

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-8, Early Online.

Posted on 2 April 2012 | 6:31 pm

(3,4-Dihydroxyphenyl)(2,3,4-trihydroxyphenyl)methanone and its derivatives as carbonic anhydrase isoenzymes inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 2 April 2012 | 6:31 pm

Design, synthesis and in vivo/in vitro screening of novel chlorokojic acid derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-12, Early Online.

Posted on 2 April 2012 | 6:31 pm

Design, synthesis of 4-aminoquinoline-derived thiazolidines and their antimalarial activity and heme polymerization inhibition studies

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-8, Early Online.

Posted on 21 March 2012 | 1:11 pm

?-secretase inhibitory activity of phenolic acid conjugated chitooligosaccharides

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-4, Early Online.

Posted on 16 March 2012 | 5:52 pm

Monoamine oxidase inhibition by monoterpene indole alkaloids and fractions obtained from Psychotria suterella and Psychotria laciniata

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-8, Early Online.

Posted on 16 March 2012 | 5:52 pm

Inhibitory effect of cisplatin and [Pt(dach)Cl2] on the activity of phospholipase A2

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-10, Early Online.

Posted on 16 March 2012 | 5:52 pm

Synthesis, antimicrobial activity and molecular modeling study of substituted 5-aryl-pyrimido[5,4-c]quinoline-2,4-diones

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-9, Early Online.

Posted on 7 March 2012 | 5:47 pm

Synthesis and anticonvulsant activity of 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2-carboxamide/carbothioamide analogues

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 7 March 2012 | 5:47 pm

Synthesis of ?-oxycarbanilinophosphonates and their anticholinesterase activities: the most potent derivative is bound to the peripheral site of acetylcholinesterase

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 7 March 2012 | 5:47 pm

Novel 1-acyl-4-substituted semicarbazide derivatives of primaquine ? synthesis, cytostatic, antiviral and antioxidative studies

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-10, Early Online.

Posted on 1 March 2012 | 4:36 pm

Design, synthesis and antihypertensive screening of novel pyridazine substituted s-triazin-2-imine/one/thione derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-8, Early Online.

Posted on 1 March 2012 | 4:36 pm

Synthesis and biological properties of C-terminal vinyl ketone pseudotripeptides

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 1 March 2012 | 4:36 pm

Design, synthesis and preliminary activity evaluation of novel 3-amino-2-hydroxyl-3-phenylpropanoic acid derivatives as aminopeptidase N/CD13 inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 1 March 2012 | 4:36 pm

Synthesis of novel carbazole chalcones as radical scavenger, antimicrobial and cancer chemopreventive agents

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-8, Early Online.

Posted on 1 March 2012 | 4:36 pm

2-(2-indolyl-)-4(3H)-quinazolines derivates as new inhibitors of AChE: design, synthesis, biological evaluation and molecular modelling

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-10, Early Online.

Posted on 1 March 2012 | 4:36 pm

Optimization of peptidyl allyl sulfones as clan CA cysteine protease inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-11, Early Online.

Posted on 1 March 2012 | 4:36 pm

Synthesis and HIV-1 RT inhibitory action of novel (4/6-substituted benzo[d]thiazol -2-yl)thiazolidin-4-ones. Divergence from the non-competitive inhibition mechanism

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-10, Early Online.

Posted on 1 March 2012 | 4:36 pm

Topoisomerase as target for antibacterial and anticancer drug discovery

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-17, Early Online.

Posted on 1 March 2012 | 4:36 pm

Identification of aldehyde dehydrogenase 1A1 modulators using virtual screening

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 1 March 2012 | 4:36 pm

Secondary/tertiary benzenesulfonamides with inhibitory action against the cytosolic human carbonic anhydrase isoforms I and II

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 1 March 2012 | 4:36 pm

Virtual screening of low molecular weight mushrooms compounds as potential Mdm2 inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 1 March 2012 | 4:36 pm

Inhibition of fatty acid synthase by ginkgolic acids from the leaves of Ginkgo biloba and their cytotoxic activity

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-4, Early Online.

Posted on 1 March 2012 | 4:36 pm

Synthesis, 2D-NMR and molecular modelling studies of pentacycloundecane lactam-peptides and peptoids as potential HIV-1 wild type C-SA protease inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-12, Early Online.

Posted on 17 February 2012 | 4:22 pm

Synthesis and in vitro antitumor and antimicrobial activity of some 2,3-diaryl-7-methyl-4,5,6,7-tetrahydroindazole and 3,3a,4,5,6,7-hexahydroindazole derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-14, Early Online.

Posted on 13 February 2012 | 5:28 pm

Impact of tautomery of 3-(4H-1,2,4-triazol-3-ylthio)-N-phenylpropanamide on the COX-1 inhibitory mechanism

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 5 February 2012 | 12:00 pm

CP-MLR/PLS directed QSAR study on the glutaminyl cyclase inhibitory activity of imidazoles: rationales to advance the understanding of activity profile

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-8, Early Online.

Posted on 5 February 2012 | 11:46 am

Synthesis and in vitro antimicrobial activity of new 4-phenyl-5-methyl-4H-1,2,4-triazole-3-thione derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-10, Early Online.

Posted on 5 February 2012 | 11:29 am

Inhibition of the ?-class carbonic anhydrases from Mycobacterium tuberculosis with carboxylic acids

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 3 February 2012 | 1:18 pm

Tumour suppressor PTEN enhanced enzyme activity of GPx, SOD and catalase by suppression of PI3K/AKT pathway in non-small cell lung cancer cell lines

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 3 February 2012 | 1:18 pm

Evaluation of a dithiocarbamate derivative as an inhibitor of human glutaredoxin-1

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 3 February 2012 | 1:18 pm

Inhibition of the alpha- and beta-carbonic anhydrases from the gastric pathogen Helycobacter pylori with anions

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-4, Early Online.

Posted on 3 February 2012 | 1:18 pm

Three new aromatic sulfonamide inhibitors of carbonic anhydrases I, II, IV and XII

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 3 February 2012 | 1:18 pm

Metronidazole-coumarin conjugates and 3-cyano-7-hydroxy-coumarin act as isoform-selective carbonic anhydrase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 3 February 2012 | 1:18 pm

Inhibition of acetylpolyamine and spermine oxidases by the polyamine analogue chlorhexidine

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 3 February 2012 | 1:18 pm

Inhibitory effect of novel pyrazole carboxamide derivatives on human carbonic anhydrase enzyme

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-9, Early Online.

Posted on 3 February 2012 | 1:18 pm

Effect of the non-steroidal anti-inflammatory drugs on the acyl-CoA synthetase activity toward medium-chain, long-chain and polyunsaturated fatty acids in mitochondria of mouse liver and brain

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 3 February 2012 | 1:18 pm

Analysis of saponins and phenolic compounds as inhibitors of ?-carbonic anhydrase isoenzymes

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 3 February 2012 | 1:18 pm

Tripeptides with non-code amino acids as potential serine proteases inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 3 February 2012 | 1:17 pm

Modulation of expression of SOD isoenzymes in mud crab (Scylla serrata): effects of inhibitors, salinity and season

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-10, Early Online.

Posted on 3 February 2012 | 1:17 pm

Synthesis and biological evaluation of some thiazole derivatives as new cholinesterase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 3 February 2012 | 1:17 pm

Investigation of heavy metal effects on immobilized paraoxanase by glutaraldehyde

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 11 January 2012 | 12:56 pm

Thioesters for the in vitro evaluation of agents to image brain cholinesterases

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-9, Early Online.

Posted on 11 January 2012 | 12:56 pm

Kinetic characterization of a slow-binding inhibitor of Bla2: thiomaltol

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 11 January 2012 | 12:56 pm

New protein farnesyltransferase inhibitors in the 3-arylthiophene 2-carboxylic acid series: diversification of the aryl moiety by solid-phase synthesis

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-9, Early Online.

Posted on 11 January 2012 | 12:56 pm

Nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors: synthesis, structure-activity relationship analysis, and biological activity

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-13, Early Online.

Posted on 11 January 2012 | 12:56 pm

Classification of difference between inhibition constants of an inhibitor to facilitate identifying the inhibition type

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-9, Early Online.

Posted on 6 January 2012 | 4:28 pm

Inhibitory properties of ibuprofen and its amide analogues towards the hydrolysis and cyclooxygenation of the endocannabinoid anandamide

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-11, Early Online.

Posted on 6 January 2012 | 4:25 pm

Synthesis and binding study of certain 6-arylalkanamides as molecular probes for cannabinoid receptor subtypes

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-4, Early Online.

Posted on 3 January 2012 | 3:09 pm

Dihalogenated sulfanilamides and benzolamides are effective inhibitors of the three ?-class carbonic anhydrases from Mycobacterium tuberculosis

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-4, Early Online.

Posted on 3 January 2012 | 3:09 pm

Sulfapyridine-like benzenesulfonamide derivatives as inhibitors of carbonic anhydrase isoenzymes I, II and VI

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 22 December 2011 | 9:00 am

Chemogenomics of pyridoxal 5?-phosphate dependent enzymes

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-12, Early Online.

Posted on 19 December 2011 | 3:01 pm

Carbonic anhydrase inhibitors: in vitro inhibition of ? isoforms (hCA I, hCA II, bCA III, hCA IV) by flavonoids

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 14 December 2011 | 4:41 pm

Novel phenyl(thio)ureas bearing (thio)oxothiazoline group as potential BACE-1 inhibitors: synthesis and biological evaluation

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-10, Early Online.

Posted on 14 December 2011 | 4:41 pm

N-Arylbenzamides: extremely simple scaffolds for the development of novel estrogen receptor agonists

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 14 December 2011 | 4:40 pm

Protective effect of cardioplegia with poly (ADP-ribose) polymerase-1 inhibitor against myocardial ischemia-reperfusion injury: in vitro study of isolated rat heart model

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 14 December 2011 | 4:39 pm

Carbonic Anhydrases inhibitory effects of new benzenesulfonamides synthesized by using superacid chemistry

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 14 December 2011 | 4:37 pm

Effect of betaine on the hepatic damage from orotic acid-induced fatty liver development in rats

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-10, Early Online.

Posted on 13 December 2011 | 1:03 pm

Heavy metal ion inhibition studies of human, sheep and fish ?-carbonic anhydrases

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 7 December 2011 | 11:22 am

Amitriptyline may have a supportive role in cancer treatment by inhibiting glutathione S-transferase pi (GST-?) and alpha (GST-?)

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 7 December 2011 | 11:21 am

Dithiocarbamates strongly inhibit the ?-class carbonic anhydrases from Mycobacterium tuberculosis

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 6 December 2011 | 5:18 pm

Simple methanesulfonates are hydrolyzed by the sulfatase carbonic anhydrase activity

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 6 December 2011 | 5:17 pm

Inhibition of mammalian carbonic anhydrase isoforms I, II and VI with thiamine and thiamine-like molecules

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-4, Early Online.

Posted on 6 December 2011 | 5:16 pm

Immunomodulatory properties of S- and N-alkylated 5-(1H-indol-2-yl)-1,3,4-oxadiazole-2(3H)-thione

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-8, Early Online.

Posted on 6 December 2011 | 5:15 pm

Synthesis, antibacterial, antielastase, antiurease and antioxidant activities of new 1,4-butylene bridged bis-1,2,4-triazole derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 6 December 2011 | 5:15 pm

Synthesis of new indole-2-carboxamide and 3-acetamide derivatives and evaluation their antioxidant properties

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 6 December 2011 | 5:13 pm

Synthesis and antibacterial activity of novel 4-chloro-2-mercaptobenzenesulfonamide derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-11, Early Online.

Posted on 6 December 2011 | 5:12 pm

Docking, CoMFA and CoMSIA studies of a series of sulfonamides derivatives as carbonic anhydrase I inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-8, Early Online.

Posted on 6 December 2011 | 5:11 pm

2-Amino-3-cyanopyridine derivatives as carbonic anhydrase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 5 December 2011 | 5:12 pm

3-Cyano-8-methyl-2-oxo-1,4-disubstituted-1,2,5,6,7,8-hexahydroquinolines. synthesis and biological evaluation as antimicrobial and cytotoxic agents

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-8, Early Online.

Posted on 3 December 2011 | 11:30 am

NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-10, Early Online.

Posted on 3 December 2011 | 11:30 am

Alkaloid profiling and anticholinesterase activity of South American Lycopodiaceae species

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 25 November 2011 | 4:26 pm

Synthesis and evaluation of substrate analogue inhibitors of trypanothione reductase

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-11, Early Online.

Posted on 15 November 2011 | 5:43 pm

Synthesis, antibacterial, antielastase, antiurease and antioxidant activities of new methoxy substitued bis-1,2,4-triazole derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 15 November 2011 | 5:43 pm

Design and synthesis of novel 2-(3-substituted propyl)-3-(2-methyl phenyl) quinazolin-4-(3H)-ones as a new class of H1-antihistaminic agents

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 10 November 2011 | 3:06 pm

In vitro enzymatic response of Turkish native chicken “Gerze” to heavy metal exposure

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 3 November 2011 | 2:12 pm

Anti-inflammatory phenolics isolated from Juniperus rigida leaves and twigs in lipopolysaccharide-stimulated RAW264.7 macrophage cells

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 3 November 2011 | 2:11 pm

Docking-based CoMFA and CoMSIA analyses of tetrahydro-?-carboline derivatives as type-5 phosphodiesterase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-14, Early Online.

Posted on 21 October 2011 | 12:31 pm

Synthesis, antimicrobial activity and cytotoxicity of some new carbazole derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 15 October 2011 | 9:00 am

BPTES inhibition of hGA124–551, a truncated form of human kidney-type glutaminase

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 15 October 2011 | 9:00 am

Carbonic anhydrase inhibitors: inhibition of human and bovine isoenzymes by benzenesulphonamides, cyclitols and phenolic compounds

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-4, Early Online.

Posted on 14 October 2011 | 8:22 pm

Prediction of estrogen receptor ? ligands potency and selectivity by docking and MM-GBSA scoring methods using three different scaffolds

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-13, Early Online.

Posted on 14 October 2011 | 8:21 pm

Computational evaluation of some indenopyrazole derivatives as anticancer compounds; application of QSAR and docking methodologies

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-17, Early Online.

Posted on 14 October 2011 | 8:20 pm

Template synthesis, spectroscopic studies, antimicrobial, nematicidal and pesticidal activities of chromium(III) macrocyclic complexes

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-8, Early Online.

Posted on 14 October 2011 | 7:50 pm

Predicting subsite interactions of plasmin with substrates and inhibitors through computational docking analysis

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 12 October 2011 | 6:07 pm

Synthesis and antibacterial activity of a new series of 3-[3-(substituted phenyl)-1-phenyl-1H-pyrazol-5-yl]-2H-chromen-2-one derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 12 October 2011 | 10:47 am

Purification of carbonic anhydrase-II from sheep liver and inhibitory effects of some heavy metals on enzyme activity

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 10 October 2011 | 6:18 pm

Assesment of metal inhibition of antioxidant enzyme glutathione reductase from rainbow trout liver

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 10 October 2011 | 6:17 pm

In vitro efficacy of some cattle drugs on bovine serum paraoxonase 1 (PON1) activity

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-8, Early Online.

Posted on 10 October 2011 | 6:16 pm

Chromone containing sulfonamides as potent carbonic anhydrase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-4, Early Online.

Posted on 10 October 2011 | 6:13 pm

Synthesis and biological evaluation of novel N, N?-disubstituted urea and thiourea derivatives as potential anti-melanoma agents

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 10 October 2011 | 6:09 pm

Ionic derivatives of betulinic acid as novel HIV-1 protease inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 10 October 2011 | 6:08 pm

Synthesis and anticonvulsant activity of some 2-(2-{1-[substituted phenyl]ethylidene}hydrazinyl)-4-(4-methoxy-phenyl)-6-oxo-1,6-dihydro-pyrimidine-5-carbonitrile

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 10 October 2011 | 11:05 am

Heterocyclic compounds as carbonic anhydrase inhibitor

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-11, Early Online.

Posted on 10 October 2011 | 11:04 am

Synthesis and biological evaluation of novel benzothiazole clubbed fluoroquinolone derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-10, Early Online.

Posted on 10 October 2011 | 11:04 am

Polyphenol fatty acid esters as serine protease inhibitors: a quantum-chemical QSAR analysis

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-10, Early Online.

Posted on 10 October 2011 | 11:04 am

Designing hypothesis of substituted benzoxazinones as HIV-1 reverse transcriptase inhibitors: QSAR approach

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-15, Early Online.

Posted on 1 October 2011 | 9:00 am

Antiobesity activity of fermented Angelicae gigantis by high fat diet-induced obese rats

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-11, Early Online.

Posted on 30 September 2011 | 8:33 pm

Studies on synthetic and structural characterization of new fluorine substituted phthalides of pharmaceutical interest

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-10, Early Online.

Posted on 15 September 2011 | 5:08 pm

In vitro and in vivo effects of some benzodiazepine drugs on human and rabbit erythrocyte carbonic anhydrase enzymes

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 15 September 2011 | 4:54 pm

Molecular docking studies of anti-apoptotic BCL-2, BCL-XL, and MCL-1 proteins with ginsenosides from Panax ginseng

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-8, Early Online.

Posted on 15 September 2011 | 4:16 pm

Syntheses and evaluation of anti-inflammatory, analgesic and ulcerogenic activities of 1,3,4-oxadiazole and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-8, Early Online.

Posted on 8 September 2011 | 12:22 pm

QSARs on human carbonic anhydrase VA and VB inhibitors of some new not yet synthesized, substituted aromatic/heterocyclic sulphonamides as anti-obesity agent

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 8 September 2011 | 12:21 pm

Synthesis and cytotoxicity studies of bifunctional hybrids of nitrogen mustards with potential enzymes inhibitors based on melamine framework

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-9, Early Online.

Posted on 8 September 2011 | 12:21 pm

Structural analysis of structurally diverse ?-glucosidase inhibitors for active site feature analysis

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-9, Early Online.

Posted on 8 September 2011 | 12:21 pm

Apoptotic, antioxidant and antiradical effects of majdine and isomajdine from Vinca herbacea Waldst. and kit

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-8, Early Online.

Posted on 2 September 2011 | 1:11 pm

Anti-cancer characteristics of mevinolin against three different solid tumor cell lines was not solely p53-dependent

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 2 September 2011 | 1:11 pm

Antiproliferative activity of some 1,4-dimethylcarbazoles on cells that express estrogen receptors: part I

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 2 September 2011 | 1:11 pm

Using C60 fullerenes for photodynamic inactivation of mosquito iridescent viruses

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-4, Early Online.

Posted on 2 September 2011 | 1:11 pm

Effects of some metals on paraoxonase activity from shark Scyliorhinus canicula

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-4, Early Online.

Posted on 2 September 2011 | 1:11 pm

Divergent effects of compounds on the hydrolysis and transpeptidation reactions of ?-glutamyl transpeptidase

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-14, Early Online.

Posted on 24 August 2011 | 4:15 pm

Pharmacophore generation and atom-based 3D-QSAR of novel quinoline-3-carbonitrile derivatives as Tpl2 kinase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-13, Early Online.

Posted on 18 August 2011 | 5:19 pm

Ranitidine induces inhibition and structural changes in sucrase

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 18 August 2011 | 5:19 pm

Pistagremic acid a new leishmanicidal triterpene isolated from Pistacia integerrima Stewart

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-3, Early Online.

Posted on 18 August 2011 | 5:19 pm

Effects of some drugs on human cord blood erythrocyte carbonic anhydrases I and II: an in vitro study

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 18 August 2011 | 5:19 pm

Design, synthesis and biological evaluation of novel quinazoline derivatives as potential anti-cancer agents

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 18 August 2011 | 5:19 pm

Synthesis and characterization of novel dioxoacridine sulfonamide derivatives as new carbonic anhydrase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 16 August 2011 | 6:10 pm

Definition of peptide inhibitors from a synthetic peptide library by targeting gelatinase B/matrix metalloproteinase-9 (MMP-9) and TNF-? converting enzyme (TACE/ADAM-17)

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-8, Early Online.

Posted on 10 August 2011 | 12:17 pm

Inhibitory alkaloids from Dictamnus dasycarpus root barks on lipopolysaccharide-induced nitric oxide production in BV2 cells

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 10 August 2011 | 12:17 pm

Effects of cysteinyl-leukotriene receptors’ antagonism by montelukast on lung mechanics and olfactory system histology in healthy mice

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 10 August 2011 | 12:17 pm

Evaluation of the inhibition of mushroom tyrosinase and cellular tyrosinase activities of oxyresveratrol: comparison with mulberroside A

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-9, Early Online.

Posted on 10 August 2011 | 12:17 pm

Inhibition of Lck: evidence for a novel natural Src family kinase inhibitor

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-7, Early Online.

Posted on 10 August 2011 | 12:17 pm

Synthesis of some N-[4-(benzothiazole-2yl) phenyl]-2-aryloxyacetamide derivatives and their anticancer activities

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-6, Early Online.

Posted on 8 August 2011 | 4:45 pm

Synthesis, biological screening and molecular modeling studies of novel 3-chloro-4-substituted-1-(2-(1H-benzimidazol-2-yl)phenyl))-azetidin-2-ones

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-5, Early Online.

Posted on 8 August 2011 | 4:45 pm

Inhibition of human carbonic anhydrase isozymes I, II and VI with a series of bisphenol, methoxy and bromophenol compounds

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-9, Early Online.

Posted on 4 August 2011 | 6:50 pm

Synthesis, characterization and in vitro antimicrobial evaluation of new compounds incorporating oxindole nucleus

Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 0, Issue 0, Page 1-10, Early Online.

Posted on 3 May 2011 | 12:31 pm

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Stichworte:
Chronologische Liste mit Fachartikeln zum Thema Chemie, Medizinische Chemie, Journal of Enzyme Inhibition and Medicinal Chemistry.
Stand:
25.04.2011
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