Organic Chemistry: Current Research Articles

 
Current articles in the field of Organic Chemistry published online in scientific journals.

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On this page considered biochemistry journals:

Beilstein Journal of Organic Chemistry - published by The Beilstein-Institut -
... in cooperation with BioMed Central - is an Open Access, peer-reviewed online journal that will encompass all aspects of organic chemistry. Full research papers and preliminary communications (short reports) will be published in the journal.

The Journal of Organic Chemistry - published by The American Chemical Society -
Original contributions reporting novel, important findings of fundamental research in all branches of the theory and practice of organic and bioorganic chemistry.

Organic Letters - published by The American Chemical Society -
Brief reports of significant research concerning organic chemistry, including organic synthesis, organometallic, natural product, physical organic, bioorganic, and medicinal chemistry.

European Journal of Organic Chemistry - published by Wiley-Interscience -
... publishes Full Papers, Short Communications, and Microreviews from the entire spectrum of synthetic organic, bioorganic and physical-organic chemistry.

Current research articles of the mentioned journals:

Organic Letters Organic Letters, Volume 10 Issue 15 (August 7, 2008) is now available Source: Organic Letters | 7 Aug 2008 | 6:00 am CEST

Toward the Synthesis of Didemnaketal B: A Convergent Synthesis of the C9−C28 Subunit Hisanaka Ito, Takaya Inoue, and Kazuo Iguchi Web Release Date: Thu, 24 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801395q Source: Organic Letters | 24 Jul 2008 | 6:00 am CEST

Stereoselectivity in the Epoxidation of Carbohydrate-Based Oxepines Shankar D. Markad, Shijing Xia, Nicole L. Snyder, Bikash Surana, Martha D. Morton, Christopher M. Hadad, and Mark W. Peczuh Web Release Date: Thu, 24 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800979a Source: The Journal of Organic Chemistry | 24 Jul 2008 | 6:00 am CEST

Studies Directed toward the Stereochemical Structure Determination of the Naturally Occurring Glucosidase Inhibitor, Kotalanol: Synthesis and Inhibitory Activities against Human Maltase Glucoamylase of Seven-Carbon, Chain-Extended Homologues of Salacinol Ravindranath Nasi, Brian O. Patrick, Lyann Sim, David R. Rose, and B. Mario Pinto Web Release Date: Thu, 24 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800855n Source: The Journal of Organic Chemistry | 24 Jul 2008 | 6:00 am CEST

Supramolecular Substitution Reactions between Hydrazide-Based Molecular Duplex Strands: Complexation Induced Nonsymmetry and Dynamic Behavior Yong Yang, Jun-Feng Xiang, Min Xue, Hai-Yu Hu, and Chuan-Feng Chen Web Release Date: Thu, 24 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo801139p Source: The Journal of Organic Chemistry | 24 Jul 2008 | 6:00 am CEST

Ab Initio and Density Functional Theory Evidence on the Rate-Limiting Step in the Morita−Baylis−Hillman Reaction Dipankar Roy and Raghavan B. Sunoj Web Release Date: Thu, 24 Jul 2008 00:00:00 EDT (Additions & Corrections) DOI: 10.1021/ol801540x Source: Organic Letters | 24 Jul 2008 | 6:00 am CEST

Energetic Differences between the Five- and Six-Membered Ring Hydrocarbons: Strain Energies in the Parent and Radical Molecules Filipe Agapito, Paulo M. Nunes, Benedito J. Costa Cabral, Rui M. Borges dos Santos, and José A. Martinho Simões Web Release Date: Thu, 24 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800690m Source: The Journal of Organic Chemistry | 24 Jul 2008 | 6:00 am CEST

Glycolipids from Sponges. 20.1 J-Coupling Analysis for Stereochemical Assignments in Furanosides: Structure Elucidation of Vesparioside B, a Glycosphingolipid from the Marine Sponge Spheciospongia vesparia Valeria Costantino, Ernesto Fattorusso, Concetta Imperatore, and Alfonso Mangoni Web Release Date: Thu, 24 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800837k Source: The Journal of Organic Chemistry | 24 Jul 2008 | 6:00 am CEST

Solid-Phase Synthesis of a Cyclodepsipeptide: Cotransin Irene Coin, Monika Beerbaum, Peter Schmieder, Michael Bienert, and Michael Beyermann Web Release Date: Thu, 24 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol800855p Source: Organic Letters | 24 Jul 2008 | 6:00 am CEST

Chemodosimetric Hg2+-Selective Signaling by Mercuration of Dichlorofluorescein Derivatives Myung Gil Choi, De Hun Ryu, Hye Lim Jeon, Sunyoung Cha, Janggeun Cho, Hyun Hye Joo, Kwan Soo Hong, Chulhyun Lee, Sangdoo Ahn, and Suk-Kyu Chang Web Release Date: Thu, 24 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol8013446 Source: Organic Letters | 24 Jul 2008 | 6:00 am CEST

Development of Highly Regioselective Amidyl Radical Cyclization Based on Lone Pair−Lone Pair Repulsion Xinting Yuan, Kun Liu, and Chaozhong Li Web Release Date: Thu, 24 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800845b Source: The Journal of Organic Chemistry | 24 Jul 2008 | 6:00 am CEST

Design of a Semirigid Molecule as a Selective Fluorescent Chemosensor for Recognition of Cd(II) Xiao-Liang Tang, Xiao-Hong Peng, Wei Dou, Jie Mao, Jiang-Rong Zheng, Wen-Wu Qin, Wei-Sheng Liu, Jin Chang, and Xiao-Jun Yao Web Release Date: Thu, 24 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801382f Source: Organic Letters | 24 Jul 2008 | 6:00 am CEST

Copper Zeolites as Green Catalysts for Multicomponent Reactions of Aldehydes, Terminal Alkynes and Amines: An Efficient and Green Synthesis of Propargylamines CuI-modified zeolites, especially CuI-USY, have proved to be very efficient catalysts in multicomponent reactions, allowing for a solvent-free synthesis of propargylamines from aldehydes, amines, and terminal alkynes. With a heterogeneous catalyst and in the absence of solvent, this process is among the greenest ever reported. A mechanism has been proposed for this three-component reaction.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) Source: European Journal of Organic Chemistry | 24 Jul 2008 | 3:49 am CEST

Aryl Trialkylsilyl Ketenes: Acid-Catalyzed Synthesis from 1-Aryl-2-diazo-2-trialkyl­silylethanones and Their Conversion into 3-Silyl-1-silyloxyallenes Aryl-substituted [alpha]-silyl [alpha]-diazo ketones are readily transformed into aryl silyl ketenes in the presence of a catalytic amount of triflic acid. Thus, a convenient method to prepare these silyl ketenes becomes available, which combines two steps, silylation of an aryl diazomethyl ketone and acid-induced Wolff rearrangement of the formed [alpha]-silyl [alpha]-diazo ketone, in a one-pot procedure. It appears that the trialkylammonium salt, which is formed in the silylation step, can also catalyze the Wolff rearrangement, but distinctly more slowly than the proton acid. The silyl ketenes react smoothly with [alpha]-silyl [alpha]-diazo ketones to form 3-silyl-1-silyloxyallenes in fairly good yields. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) Source: European Journal of Organic Chemistry | 24 Jul 2008 | 3:49 am CEST

Use of Enantiomerically Pure 7-Azabicyclo[2.2.1]heptan-2-ol as a Chiral Template for the Synthesis of Aminocyclitols Ganesh Pandey, Keshri Nath Tiwari, and V. G. Puranik Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801381t Source: Organic Letters | 23 Jul 2008 | 6:00 am CEST

Sequential Removal of Photolabile Protecting Groups for Carbonyls with Controlled Wavelength Pengfei Wang, Yun Wang, Huayou Hu, Cierra Spencer, Xing Liang, and Lurong Pan Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo8008275 Source: The Journal of Organic Chemistry | 23 Jul 2008 | 6:00 am CEST

Stereoselective Preparation of Dienol Phosphates from α,β-Ethylenic Aldehydes Gérard Cahiez, Vanessa Habiak, and Olivier Gager Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Note) DOI: 10.1021/jo800865z Source: The Journal of Organic Chemistry | 23 Jul 2008 | 6:00 am CEST

2-Pyridylnitrene from Tetrazolo[1,5-a]pyridine and Pyrido[2,3-a][1,2,4]oxadiazol-2-one Adam McCluskey and Curt Wentrup Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800899t Source: The Journal of Organic Chemistry | 23 Jul 2008 | 6:00 am CEST

Synthesis, Photochromic Properties, and Light-Controlled Metal Complexation of a Naphthopyran Derivative Satish Kumar, David Hernandez, Brenda Hoa, Yuna Lee, Julie S. Yang, and Alison McCurdy Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801406b Source: Organic Letters | 23 Jul 2008 | 6:00 am CEST

pH-Dependent, Stereoselective Dimerization of Sinomenine Zhang-Shuang Deng, Yu Zhao, Cui-Cui He, Jie Jin, Yun-Mian He, and Jian-Xin Li Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801403k Source: Organic Letters | 23 Jul 2008 | 6:00 am CEST

Asymmetric Addition of Dimethylzinc to α-Ketoesters Catalyzed by (−)-MITH Hsyueh-Liang Wu, Ping-Yu Wu, Ying-Ying Shen, and Biing-Jiun Uang Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Note) DOI: 10.1021/jo801034q Source: The Journal of Organic Chemistry | 23 Jul 2008 | 6:00 am CEST

A Straightforward Synthesis of Tetrameric Estrone-Based Macrocycles Pedro Ramírez-López, María C. de la Torre, Hector E. Montenegro, María Asenjo, and Miguel A. Sierra Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801313g Source: Organic Letters | 23 Jul 2008 | 6:00 am CEST

Design of a Coumarin-Based Triketone as a Fluorescent Protecting Group for Primary Amines Pei-Yu Kuo and Ding-Yah Yang Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Note) DOI: 10.1021/jo801060p Source: The Journal of Organic Chemistry | 23 Jul 2008 | 6:00 am CEST

Origin of Stereoselectivity in the Reduction of a Planar Oxacarbenium Joann M. Um, K. N. Houk, and Andrew J. Phillips Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801421n Source: Organic Letters | 23 Jul 2008 | 6:00 am CEST

Radical, One-Step Approach to o-Chlorophenyl Thioethers from Xanthates. A Rapid Access to Vinylsilanes Matthieu Corbet, Zorana Ferjančić, Béatrice Quiclet-Sire, and Samir Z. Zard Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801348u Source: Organic Letters | 23 Jul 2008 | 6:00 am CEST

Modular Functional Integration of a Two-Input INH Logic Gate with a Fluorophore−Spacer−Receptor1−Spacer−Receptor2 Conjugate Marek Kluciar, Rita Ferreira, Baltazar de Castro, and Uwe Pischel Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800342t Source: The Journal of Organic Chemistry | 23 Jul 2008 | 6:00 am CEST

Cladoniamides A−G, Tryptophan-Derived Alkaloids Produced in Culture by Streptomyces uncialis David E. Williams, Julian Davies, Brian O. Patrick, Helen Bottriell, Tamsin Tarling, Michel Roberge, and Raymond J. Andersen Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801274c Source: Organic Letters | 23 Jul 2008 | 6:00 am CEST

Stereoselective Synthesis of 3-Alkyl-2-aryltetrahydrofuran-4-ols: Total Synthesis of (±)-Paulownin Steven R. Angle, Inchang Choi, and Fook S. Tham Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800901r Source: The Journal of Organic Chemistry | 23 Jul 2008 | 6:00 am CEST

Brevisamide: An Unprecedented Monocyclic Ether Alkaloid from the Dinoflagellate Karenia brevis That Provides a Potential Model for Ladder-Frame Initiation Masayuki Satake, Andrea J. Bourdelais, Ryan M. Van Wagoner, Daniel G. Baden, and Jeffrey L. C. Wright Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801243n Source: Organic Letters | 23 Jul 2008 | 6:00 am CEST

Convergent Synthesis and Biological Activity of the WXYZA′B′C′ Ring System of Maitotoxin Tohru Oishi, Futoshi Hasegawa, Kohei Torikai, Keiichi Konoki, Nobuaki Matsumori, and Michio Murata Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801369g Source: Organic Letters | 23 Jul 2008 | 6:00 am CEST

CAN-Mediated Highly Regio- and Stereoselective Oxidation of Vinylidenecyclopropanes: A Novel Method for the Synthesis of Unsymmetrical Divinyl Ketone and Functional Enone Derivatives Chenliang Su, Xian Huang, and Qingyang Liu Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Note) DOI: 10.1021/jo800829a Source: The Journal of Organic Chemistry | 23 Jul 2008 | 6:00 am CEST

Copper(II)−Bis(oxazoline) Catalyzed Asymmetric Diels−Alder Reaction with α′-Arylsulfonyl Enones as Dienophiles Santiago Barroso, Gonzalo Blay, Lina Al-Midfa, M. Carmen Muñoz, and José R. Pedro Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Note) DOI: 10.1021/jo8009227 Source: The Journal of Organic Chemistry | 23 Jul 2008 | 6:00 am CEST

Organocatalytic Asymmetric Addition of Alcohols and Thiols to Activated Electrophiles: Efficient Dynamic Kinetic Resolution and Desymmetrization Protocols Aldo Peschiulli, Cormac Quigley, Seán Tallon, Yuri K. Gun’ko, and Stephen J. Connon Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Note) DOI: 10.1021/jo801158g Source: The Journal of Organic Chemistry | 23 Jul 2008 | 6:00 am CEST

Coupling Reactions of Bromoalkynes with Imidazoles Mediated by Copper Salts: Synthesis of Novel N-Alkynylimidazoles Christophe Laroche, Jing Li, Matthew W. Freyer, and Sean M. Kerwin Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Note) DOI: 10.1021/jo801118q Source: The Journal of Organic Chemistry | 23 Jul 2008 | 6:00 am CEST

A Computational Study of Lithium Ketone Enolate Aggregation in the Gas Phase and in THF Solution Lawrence M. Pratt, Son C. Nguyen, and Bui T. Thanh Web Release Date: Wed, 23 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800528y Source: The Journal of Organic Chemistry | 23 Jul 2008 | 6:00 am CEST

Vanadium(V) Salen Complex Catalyzed Highly Enantioselective Cyanoformylation of Aldehydes in the Presence of Imidazole as a Cocatalyst Highly enantioselective cyanoformylation of aldehydes catalyzed by VV chiral salen complex by using ethyl cyanoformate as a source of cyanide was accomplished in the presence of several cocatalysts. Excellent yields and ee values for the resulting cyanohydrin carbonates were achieved when imidazole was used as a cocatalyst at -20 °C. The ee value of the cyanohydrin carbonate of 2-naphthaldehyde was further improved to >99 % by recrystallization. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) Source: European Journal of Organic Chemistry | 23 Jul 2008 | 4:10 am CEST

Reactivity of (Mono-tert-butyloxiranyl)lithium: A Theoretical Ab Initio Study The reactivity of the lithiated tert-butyloxiranyl anion has been studied by means of ab initio calculations at the CCSD(T)//MP2 level of theory. Four reaction paths have been studied (three ring-opening reactions and one addition reaction). All extrema were located and characterised. The effects of solvation by one or two MeLi molecules were studied for each reaction path by reoptimising the various extrema. It was found that the addition reaction path becomes competitive when at least two MeLi molecules are taken into account. This shows the catalytic effect of alkyllithium on this reaction path. In no case could a free carbene be characterised as a reaction intermediate. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) Source: European Journal of Organic Chemistry | 23 Jul 2008 | 4:10 am CEST

Small Band Gap Oligothieno[3,4-b]pyrazines Bram P. Karsten and René A. J. Janssen Web Release Date: Tue, 22 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol8012638 Source: Organic Letters | 22 Jul 2008 | 6:00 am CEST

Preparation of a Functionalized Tetracyclic Intermediate for the Synthesis of Rhodexin A Michael E. Jung and Hiufung V. Chu Web Release Date: Tue, 22 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801426z Source: Organic Letters | 22 Jul 2008 | 6:00 am CEST

α-Pyridylation of Chiral Amines via Urea Coupling, Lithiation and Rearrangement Jonathan Clayden and Ulrich Hennecke Web Release Date: Tue, 22 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801332n Source: Organic Letters | 22 Jul 2008 | 6:00 am CEST

A Biomimetic Approach for Polyfunctional Secocholanes: Tuning Flexibility and Functionality on Peptidic and Macrocyclic Scaffolds Derived from Bile Acids Daniel G. Rivera, Orlando Pando, Rayser Bosch, and Ludger A. Wessjohann Web Release Date: Tue, 22 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800708m Source: The Journal of Organic Chemistry | 22 Jul 2008 | 6:00 am CEST

Planar Tetracoordinate Carbons in Cyclic Semisaturated Hydrocarbons Nancy Perez-Peralta, Mario Sanchez, Jesus Martin-Polo, Rafael Islas, Alberto Vela, and Gabriel Merino Web Release Date: Tue, 22 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800885x Source: The Journal of Organic Chemistry | 22 Jul 2008 | 6:00 am CEST

An Efficient Preparation of β-Aryl-β-ketophosphonates by the TFAA/H3PO4-Mediated Acylation of Arenes with Phosphonoacetic Acids George P. Luke, Christopher K. Seekamp, Zhe-Qing Wang, and Bertrand L. Chenard Web Release Date: Tue, 22 Jul 2008 00:00:00 EDT (Note) DOI: 10.1021/jo800973e Source: The Journal of Organic Chemistry | 22 Jul 2008 | 6:00 am CEST

Stereomutation of Conformational Enantiomers of 9-Isopropyl-9-formylfluorene and Related Acyl Derivatives Daniele Casarini, Lodovico Lunazzi, and Andrea Mazzanti Web Release Date: Tue, 22 Jul 2008 00:00:00 EDT (Note) DOI: 10.1021/jo8008897 Source: The Journal of Organic Chemistry | 22 Jul 2008 | 6:00 am CEST

Synthesis of Perylene-3,4-mono(dicarboximide)−Fullerene C60 Dyads as New Light-Harvesting Systems Jérôme Baffreau, Lucie Ordronneau, Stéphanie Leroy-Lhez, and Piétrick Hudhomme Web Release Date: Tue, 22 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800804z Source: The Journal of Organic Chemistry | 22 Jul 2008 | 6:00 am CEST

ZrCl4 as an Efficient Catalyst for a Novel One-Pot Protection/Deprotection Synthetic Methodology Surendra Singh, Colm D. Duffy, Syed Tasadaque A. Shah, and Patrick J. Guiry Web Release Date: Tue, 22 Jul 2008 00:00:00 EDT (Note) DOI: 10.1021/jo800932t Source: The Journal of Organic Chemistry | 22 Jul 2008 | 6:00 am CEST

Sterically Biased 3,3-Sigmatropic Rearrangement of Chiral Allylic Azides: Application to the Total Syntheses of Alkaloids Sophie Lauzon, François Tremblay, David Gagnon, Cédrickx Godbout, Christine Chabot, Catherine Mercier-Shanks, Stéphane Perreault, Hélène DeSève, and Claude Spino Web Release Date: Tue, 22 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800817p Source: The Journal of Organic Chemistry | 22 Jul 2008 | 6:00 am CEST

Synthesis, Optical Properties, and LFER Analysis of Solvent-Dependent Binding Constants of Hamilton-Receptor-Connected Merocyanine Chromophores Johann Schmidt, Ralf Schmidt, and Frank Würthner Web Release Date: Tue, 22 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo801083b Source: The Journal of Organic Chemistry | 22 Jul 2008 | 6:00 am CEST

Solution-Phase Synthesis of First-Generation Tetraester Dendritic Branches Involving Microwave and/or Ultrasonic Irradiation Trifunctionalized aromatic cores were selectively protected to obtain precursors for bidirectional dendritic unit growth through stepwise divergent syntheses. The synthesis of first-generation dendrimer building blocks was performed by nucleophilic substitution of bromomethyl-substituted aromatic cores with diethyl malonate anions in the presence of carbonate in halogen-free solvents. The screening of the reaction parameters revealed the optimum conditions for small- and larger-scale synthesis: these require microwave or ultrasonic irradiation to achieve yields around 70 % in reaction times as short as 15 min. As a result of the heterogeneity of the reaction mixtures, efficient stirring was important to suppress byproduct formation.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) Source: European Journal of Organic Chemistry | 21 Jul 2008 | 7:36 am CEST

Organocatalytic Three-Component Reactions of Pyruvate, Aldehyde and Aniline by Hydrogen-Bonding Catalysts Hydrogen-bonding catalysts have been found to catalyze one-pot three-component reactions of pyruvate, anilines and aldehydes to afford versatile 3-amino-1,5-dihydro-2H-pyrrol-2-ones in high yields. Both, thioureas and phosphoric acids are viable catalysts for these reactions and have comparable activity. The corresponding chiral thioureas and phosphoric acids have also been used in these three-component reactions to give pyrrol-2-ones in high yields and with moderate enantioselectivities.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) Source: European Journal of Organic Chemistry | 21 Jul 2008 | 7:36 am CEST

Synthesis of 2,3- and 3,4-Methanoamino Acid Equivalents with Stereochemical Diversity and Their Conversion into the Tripeptide Proteasome Inhibitor Belactosin A and Its Highly Potent Cis-Cyclopropane Stereoisomer Keisuke Yoshida, Kazuya Yamaguchi, Takayuki Sone, Yuka Unno, Akira Asai, Hideyoshi Yokosawa, Akira Matsuda, Mitsuhiro Arisawa, and Satoshi Shuto Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol8013304 Source: Organic Letters | 19 Jul 2008 | 6:00 am CEST

Efficient Sequential Segment Coupling Using N-Alkylcysteine-Assisted Thioesterification for Glycopeptide Dendrimer Synthesis Chinatsu Ozawa, Hidekazu Katayama, Hironobu Hojo, Yuko Nakahara, and Yoshiaki Nakahara Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801340m Source: Organic Letters | 19 Jul 2008 | 6:00 am CEST

Highly Electron-Donating 3,3′-Diaryl-1,1′-bi(isobenzofuran)s Synthesized by Photochemical Exocyclic [2 + 2 + 2] Cycloaddition Hongyu Zhang, Atsushi Wakamiya, and Shigehiro Yamaguchi Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801358c Source: Organic Letters | 19 Jul 2008 | 6:00 am CEST

A Versatile Cyclodehydration Reaction for the Synthesis of Isoquinoline and β-Carboline Derivatives Mohammad Movassaghi and Matthew D. Hill Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801264u Source: Organic Letters | 19 Jul 2008 | 6:00 am CEST

Organocatalytic Stereoselective Mannich Reaction of 3-Substituted Oxindoles Xu Tian, Kun Jiang, Jing Peng, Wei Du, and Ying-Chun Chen Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801351j Source: Organic Letters | 19 Jul 2008 | 6:00 am CEST

Total Synthesis of GEX1A Timothy J. Murray and Craig J. Forsyth Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol800902g Source: Organic Letters | 19 Jul 2008 | 6:00 am CEST

“Lock and Key Control” of Photochromic Reactivity by Controlling the Oxidation/Reduction State Xiaochuan Li, Yuzhen Ma, Bingcai Wang, and Gongan Li Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol8013655 Source: Organic Letters | 19 Jul 2008 | 6:00 am CEST

A Novel Access to Tetrahydro-β-Carbolines via One-Pot Hydroformylation/Fischer Indole Synthesis: Rearrangement of 3,3-Spiroindoleninium Cations Bojan P. Bondzić and Peter Eilbracht Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801071y Source: Organic Letters | 19 Jul 2008 | 6:00 am CEST

Pd-Catalyzed Borylative Polycyclization of Enediynes to Allylboronates Juan Marco-Martínez, Elena Buñuel, Rebeca Muñoz-Rodríguez, and Diego J. Cárdenas Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801424m Source: Organic Letters | 19 Jul 2008 | 6:00 am CEST

Total Synthesis of Aristolactams via a One-Pot Suzuki−Miyaura Coupling/Aldol Condensation Cascade Reaction Joa Kyum Kim, Young Ha Kim, Ho Tae Nam, Bum Tae Kim, and Jung-Nyoung Heo Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801291k Source: Organic Letters | 19 Jul 2008 | 6:00 am CEST

Syntheses and Biological Evaluation of B-Ring-Modified Analogues of Dafachronic Acid A Simon Giroux, Axel Bethke, Nicole Fielenbach, Adam Antebi, and E. J. Corey Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801425v Source: Organic Letters | 19 Jul 2008 | 6:00 am CEST

Consecutive Cyclization of Allylaminoalkene by Intramolecular Aminolithiation−Carbolithiation Susumu Tsuchida, Atsunori Kaneshige, Tokutaro Ogata, Hiromi Baba, Yasutomo Yamamoto, and Kiyoshi Tomioka Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801397v Source: Organic Letters | 19 Jul 2008 | 6:00 am CEST

Magnesium Nitride as a Convenient Source of Ammonia: Preparation of Primary Amides Gemma E. Veitch, Katy L. Bridgwood, and Steven V. Ley Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801398z Source: Organic Letters | 19 Jul 2008 | 6:00 am CEST

On the Two-Ligand Catalytic Asymmetric Deprotonation of N-Boc Pyrrolidine: Probing the Effect of the Stoichiometric Ligand Julia L. Bilke and Peter O’Brien Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Note) DOI: 10.1021/jo8010655 Source: The Journal of Organic Chemistry | 19 Jul 2008 | 6:00 am CEST

Magnesium Nitride as a Convenient Source of Ammonia: Preparation of Dihydropyridines Katy L. Bridgwood, Gemma E. Veitch, and Steven V. Ley Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801399w Source: Organic Letters | 19 Jul 2008 | 6:00 am CEST

Rational or Statistical Routes from 1-Acyldipyrromethanes to meso-Substituted Porphyrins. Distinct Patterns, Multiple Pyridyl Substituents, and Amphipathic Architectures Dilek Kiper Dogutan, Marcin Ptaszek, and Jonathan S. Lindsey Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800588n Source: The Journal of Organic Chemistry | 19 Jul 2008 | 6:00 am CEST

Formal Total Synthesis of (+)-Gephyrotoxin Marco Santarem, Corinne Vanucci-Bacqué, and Gérard Lhommet Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Note) DOI: 10.1021/jo801150e Source: The Journal of Organic Chemistry | 19 Jul 2008 | 6:00 am CEST

Microwave-Enhanced Ionothermal CuAAC for the Synthesis of Glycoclusters on a Calix[4]arene Platform Alessandra Vecchi, Bernardo Melai, Alberto Marra, Cinzia Chiappe, and Alessandro Dondoni Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Note) DOI: 10.1021/jo800954z Source: The Journal of Organic Chemistry | 19 Jul 2008 | 6:00 am CEST

Probing the Importance of the Hemilabile Site of Bis(phosphine) Monoxide Ligands in the Copper-Catalyzed Addition of Diethylzinc to N-Phosphinoylimines: Discovery of New Effective Chiral Ligands Isabelle Bonnaventure and André B. Charette Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800969x Source: The Journal of Organic Chemistry | 19 Jul 2008 | 6:00 am CEST

Co-Complexes Derived from Alkene Insertion to Alkyne-Dicobaltpentacarbonyl Complexes: Insight into the Regioselectivity of Pauson−Khand Reactions of Cyclopropenes Mahesh K. Pallerla, Glenn P. A. Yap, and Joseph M. Fox Web Release Date: Sat, 19 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800776z Source: The Journal of Organic Chemistry | 19 Jul 2008 | 6:00 am CEST

Synthesis of Carbasugar C-1 Phosphates via Pd-Catalyzed Cyclopropanol Ring Opening Mingde Shan and George A. O’Doherty Web Release Date: Fri, 18 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801106r Source: Organic Letters | 18 Jul 2008 | 6:00 am CEST

Asymmetric Synthesis of Tetracyclic Benzo[a]quinolizidine Targets Steven M. Allin, Sean N. Gaskell, Mark R. J. Elsegood, and William P. Martin Web Release Date: Fri, 18 Jul 2008 00:00:00 EDT (Note) DOI: 10.1021/jo801019h Source: The Journal of Organic Chemistry | 18 Jul 2008 | 6:00 am CEST

Flexible Strategy for the Synthesis of Pyrrolizidine Alkaloids Timothy J. Donohoe, Rhian E. Thomas, Matthew D. Cheeseman, Caroline L. Rigby, Gurdip Bhalay, and Ian D. Linney Web Release Date: Fri, 18 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801415d Source: Organic Letters | 18 Jul 2008 | 6:00 am CEST

The Journal of Organic Chemistry The Journal of Organic Chemistry, Volume 73 Issue 14 (July 18, 2008) is now available Source: The Journal of Organic Chemistry | 18 Jul 2008 | 6:00 am CEST

Convergent and Rapid Assembly of Substituted 2-Pyridones through Formation of N-Alkenyl Alkynylamides Followed by Gold-Catalyzed Cycloisomerization Hidetomo Imase, Keiichi Noguchi, Masao Hirano, and Ken Tanaka Web Release Date: Fri, 18 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol801466f Source: Organic Letters | 18 Jul 2008 | 6:00 am CEST

Unusual Reactions Between Aromatic Carbon Supernucleophiles and 1,2-Diazabuta-1,3-dienes: Useful Routes to New Pyrazolone and Cinnoline Derivatives Reactions between 1,3,5-tris(dialkylamino)benzenes and 1,2-diazabuta-1,3-dienes produce semicarbazone derivatives through attack of the supernucleophile aromatic carbon atom at the terminal carbon atom of the heterodiene reagent. The strong activation of the aromatic ring due to the presence of the three amino groups in a symmetrical relationship promotes electrophilic aromatic substitution by the neutral carbon atom of the electrophile. The resulting semicarbazones, in methanol in the presence of sodium methoxide, mainly afford pyrazolone derivatives, whereas in THF in the presence of sodium methoxide an unusual cyclization reaction produces cinnoline derivatives as the major products. Both cyclization reaction mechanisms are discussed.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) Source: European Journal of Organic Chemistry | 17 Jul 2008 | 7:35 am CEST

Phosphotungstic Acid Catalyzed Amidation of Alcohols Mild nucleophilic substitution reactions of benzhydrylic, benzylic, allylic, and simple aliphatic alcohols with sulfonamides, benzamide, and 4-nitroaniline in the presence of 12-phosphotungstic acid as an efficient, eco-friendly, cheap, and air- and moisture-tolerant catalyst for the construction of C-N bonds has been investigated. The amine derivatives were obtained in good yields (up to 98 %). The reusable nature of the 12-phosphotungstic acid makes this protocol more attractive.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) Source: European Journal of Organic Chemistry | 17 Jul 2008 | 7:35 am CEST

Germanium(II)-Mediated Reductive Cross-Aldol Reaction of Bromoaldehydes with Aldehydes: NMR Studies and ab Initio Calculations Shin-ya Tanaka, Nobuo Tagashira, Kouji Chiba, Makoto Yasuda, and Akio Baba Web Release Date: Thu, 17 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800904u Source: The Journal of Organic Chemistry | 17 Jul 2008 | 6:00 am CEST

Total Synthesis of (−)-Bitungolide F and Determination of its Absolute Stereochemistry Subhash Ghosh, Soma Uday Kumar, and J. Shashidhar Web Release Date: Thu, 17 Jul 2008 00:00:00 EDT (Addition/Correction) DOI: 10.1021/jo801320u Source: The Journal of Organic Chemistry | 17 Jul 2008 | 6:00 am CEST

Synthesis of Fullerooxazoles: Novel Reactions of [60]Fullerene with Nitriles Promoted by Ferric Perchlorate Fa-Bao Li, Tong-Xin Liu, and Guan-Wu Wang Web Release Date: Thu, 17 Jul 2008 00:00:00 EDT (Note) DOI: 10.1021/jo8007868 Source: The Journal of Organic Chemistry | 17 Jul 2008 | 6:00 am CEST

Aminoferrocene Lithiation by Boron Trifluoride Activation Costa Metallinos, Josh Zaifman, and Laura Dodge Web Release Date: Thu, 17 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol8013182 Source: Organic Letters | 17 Jul 2008 | 6:00 am CEST

A Concise Synthesis of the Pentacyclic Framework of Cortistatins Shuji Yamashita, Kentaro Iso, and Masahiro Hirama Web Release Date: Thu, 17 Jul 2008 00:00:00 EDT (Letter) DOI: 10.1021/ol8012099 Source: Organic Letters | 17 Jul 2008 | 6:00 am CEST

Soft Metal-Mediated Base Pairing with Novel Synthetic Nucleosides Possessing an O,S-Donor Ligand Yusuke Takezawa, Kentaro Tanaka, Maiko Yori, Shohei Tashiro, Motoo Shiro, and Mitsuhiko Shionoya Web Release Date: Thu, 17 Jul 2008 00:00:00 EDT (Article) DOI: 10.1021/jo800587d Source: The Journal of Organic Chemistry | 17 Jul 2008 | 6:00 am CEST